Endocrine Abstracts

Oestrogens are essential regulators of fertility in women. They induce changes in uterine cell function by binding to oestrogen receptors (ERs) two of which (ERα and ERß) have been identified. ERα and ERß share significant sequence homology with three other steroid receptor superfamily members that are known as oestrogen related receptors alpha (ERRα), beta (ERRß) and gamma (ERRγ). ERRs bind as monomers to the sequence TNAAGGTCA and as dimers...